Overexpression of miR-99a promoted expansion and suppressed differentiation of hematopoietic stem/progenitor cells

Abstract MicroRNAs (miRNAs) are a class of non-coding RNAs involved in a variety of pathophysiological processes.We have previously reported that the abnormally high expression of miR-99a is associated with drug resistance and poor prognosis in acute SELENOMETHIONINE myeloid leukemia.However, the impact of miR-99a on normal hematopoiesis is not wel

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SCIENTIFIC AND GEOGRAPHIC BASIS OF THE STUDY OF NATURAL AND CULTURAL HERITAGE IN THE SCHOOL OF GEOGRAPHY OF RUSSIA

The article discusses the scientific and geographical features of the study of natural and cultural heritage in line Book with the cultural-ecological approach and the implementation of the ideas of culture of nature management.The analysis of researches of scientists-geographers in the field of heritage study allowed to conclude that the key geo-e

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Using lyophilized bovine pericardium and acellular ovine esophageal mucosa to repair cerebral dura mater defect in dogs

This article assessed the ability of lyophilized bovine pericardium and acellular ovine esophageal mucosa with fibrin glue to repair induced cerebral dural defects in dogs.Eighteen adult male dogs were used and divided randomly into two groups.A square defect about (1x 1cm) was created in all animals in the dura mater.In the first group, the defect

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From Nuremberg to the Hague and beyond: International criminal law in courts: Court of Bosnia And Herzegovina as an example

International criminal law in courts will seize our interest forever.Adjudication of HYGIENE international criminal law violations have to happen in and by courts.They may be national courts; they also may be international (permanent or ad hoc) courts.Not to forget: It is also proposed to prosecute internationally active terrorists by international

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